Volume 2, Issue 1

2 articles · Published August 2026

Original Article 16 Aug 2026

Assessing the Relationship Between Placental Grading and Pregnancy Complications

Background: Placental development plays a fundamental role in ensuring a successful pregnancy. The placenta performs essential physiological, immunological, and endocrine functions and facilitates the exchange of gases between the maternal and fetal circulations. Aim: This study aimed to assess the impact of placental maturity on pregnancy outcomes among pregnant women in Najaf City. Setting and Design: A purposive sample of 100 pregnant women diagnosed at Al-Zahraa Teaching Hospital and Private Clinics in Najaf City was included in this study. Materials and Methods: Data were obtained from obstetric ultrasound examinations, patients’ medical records, and a structured data collection tool specifically developed for the purposes of this study. Statistical Analysis: Statistical analysis was performed using the Statistical Package for the Social Sciences (SPSS version 20). Descriptive statistics and correlation analyses were conducted to evaluate the relationship between placental maturity and pregnancy outcomes. Results: Cesarean section was performed in 62% of the women. Anemia was reported in 93% of the participants, while 87% of women with pregnancy-induced hypertension were diagnosed with preeclampsia, severe preeclampsia, chronic hypertension, or gestational hypertension. Among the neonates, 87% had intrauterine growth restriction (IUGR), 68% were delivered by cesarean section, and 80% required neonatal resuscitation. Conclusion: The findings demonstrated that 85% of the participants were between 36 and 39 weeks of gestation. Placental grade was significantly associated with gestational age, neonatal resuscitation, stillbirth, gestational hypertension, and meconium.

Husham K. Mankhi
Intrauterine growth restriction placenta, placental grading placental maturity
Original Article 16 Aug 2026

Determination of Antioxidant and Anticancer Potential of Chrysin Extracted from Local Propolis

Background: Chrysin is a naturally occurring flavonoid found in propolis and is well known for its diverse pharmacological properties, particularly its antioxidant and potential anticancer activities. This study investigated the extraction of propolis using different solvents and assessed the biological activities of the obtained extracts as well as the isolated chrysin. Methods: Propolis samples obtained that were extracted using ethanol, methanol, and chloroform. The extraction efficiency of each solvent was compared, and the chrysin content of the resulting extracts was quantified. In addition, the in vitro biological activities of the ethanolic propolis extract, purified chrysin, and isolated chrysin were evaluated by determining their cytotoxic effects against HeLa and MCF-7 cell lines, together with their antioxidant capacities. Results: Among the tested solvents, ethanol showed the highest extraction efficiency, followed by methanol, whereas chloroform produced the lowest extraction yield. Consequently, the ethanolic extract contained the greatest concentration of chrysin (3.764 ± 0.14 mg/g), confirming its superior extraction capability. All tested samples exhibited concentration-dependent inhibitory effects against both HeLa and MCF-7 cancer cell lines, with standard chrysin producing the strongest cytotoxic activity. Likewise, antioxidant activity increased with increasing concentration for all tested materials, while standard chrysin demonstrated the highest antioxidant effect (49.32% ± 9.90). Significant differences were observed among the tested groups. Conclusion: The findings indicate that ethanol is the most effective solvent for extracting chrysin-rich propolis. Moreover, both the ethanolic propolis extract and the isolated chrysin exhibited remarkable in vitro antioxidant and anticancer activities, supporting their potential as promising natural therapeutic agents.

Husham K. Mankhi, Manaf A. Abid
Anticancer activity antioxidant activity chrysin DPPH assay